235135 Corticosterone - CAS 50-22-6 - Calbiochem

235135
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      개요

      Replacement Information

      주요 사양표

      Empirical FormulaCAS #
      C₂₁H₃₀O₄ 50-22-6

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      235135-1GMCN
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          Plastic ampoule 1 gm
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          Description
          OverviewCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered expression which eventually affects ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
          Catalogue Number235135
          Brand Family Calbiochem®
          Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
          References
          ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
          DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
          Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
          Product Information
          CAS number50-22-6
          ATP CompetitiveN
          FormOff-white crystalline powder
          Hill FormulaC₂₁H₃₀O₄
          Chemical formulaC₂₁H₃₀O₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetMineralocorticoid and glucocorticoid receptors
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSGM7650000
          Safety Information
          R PhraseR: 62-63

          Possible risk of impaired fertility.
          Possible risk of harm to the unborn child.
          S PhraseS: 22-36

          Do not breathe dust.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Corticosterone - CAS 50-22-6 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Corticosterone - CAS 50-22-6 - Calbiochem Certificates of Analysis

          TitleLot Number
          235135

          References

          참고문헌 보기
          Garvy, B.A., et al. 1993. Immunology 80, 587.
          DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
          Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-May-2019 JSW
          Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
          DescriptionCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered genomic expression. Steroid-induced changes in protein synthesis eventually affect ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
          FormOff-white crystalline powder
          CAS number50-22-6
          RTECSGM7650000
          Chemical formulaC₂₁H₃₀O₄
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityEthanol (50 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          Merck USA index14, 2538
          ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
          DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
          Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.