124015 InSolution™ Akt Inhibitor IV - Calbiochem

124015
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      가격 및 재고 조회

      개요

      Replacement Information

      주요 사양표

      Empirical Formula
      C₃₁H₂₇IN₄S

      가격 및 재고여부

      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      124015-1MGCN
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          Plastic ampoule 1 mg
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          Description
          Catalogue Number124015
          Brand Family Calbiochem®
          References
          ReferencesKau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.


          Product Information
          ATP CompetitiveN
          FormLiquid
          FormulationA 10 mM (1 mg/163 µl) solution of Akt Inhibitor IV (Cat. No. 124011) in DMSO.
          Hill FormulaC₃₁H₂₇IN₄S
          Chemical formulaC₃₁H₂₇IN₄S
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetAkt
          Primary Target IC<sub>50</sub>625 nM and <1.25 µM in blocking Akt-mediated FOXO1a nuclear export and cell proliferation, respectively, in 786-O cells
          Purity≥98% by HPLC
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Irritant
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          InSolution™ Akt Inhibitor IV - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          InSolution™ Akt Inhibitor IV - Calbiochem Certificates of Analysis

          TitleLot Number
          124015

          References

          참고문헌 보기
          Kau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.


          Brochure

          Title
          Akt
          Biologics 31.1
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-April-2008 RFH
          DescriptionA cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC50 = 625 nM) and cell proliferation (IC50 < 1.25 µM) in 786-O cells. Unlike phosphatidylinositol analog-based Akt inhibitors (Cat. Nos. 124005, 124008, 124009), this inhibitor does not affect PI3K.
          FormLiquid
          FormulationA 10 mM (1 mg/163 µl) solution of Akt Inhibitor IV (Cat. No. 124011) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          Concentration Label Please refer to vial label for lot-specific concentration
          Chemical formulaC₃₁H₂₇IN₄S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Toxicity Irritant
          ReferencesKau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.