234491 InSolution™ PD 153035 - Calbiochem

234491
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      개요

      Replacement Information

      주요 사양표

      Empirical Formula
      C₁₆H₁₄BrN₃O₂

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      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      234491-500UGCN
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          Plastic ampoule 500 μg
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          Description
          Catalogue Number234491
          Brand Family Calbiochem®
          References
          Product Information
          ATP CompetitiveY
          DeclarationSold under license of U.S. Patent 5,457,105 and European Patent 0,566,266.
          FormLiquid
          FormulationA 10 mM (500 µg/139 µl) solution of PD 153035 (Cat. No. 234490) in DMSO.
          Hill FormulaC₁₆H₁₄BrN₃O₂
          Chemical formulaC₁₆H₁₄BrN₃O₂
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetEGFR
          Primary Target IC<sub>50</sub>25 pM
          Primary Target K<sub>i</sub>6 pM against the tyrosine kinase activity of the epidermal growth factor receptor (EGFR)
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Irritant
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          InSolution™ PD 153035 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          InSolution™ PD 153035 - Calbiochem Certificates of Analysis

          TitleLot Number
          234491
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-June-2008 RFH
          DescriptionAn extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; Ki = 6 pM). Rapidly suppresses autophosphorylation of EGFR at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells. Also selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation.
          FormLiquid
          FormulationA 10 mM (500 µg/139 µl) solution of PD 153035 (Cat. No. 234490) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₆H₁₄BrN₃O₂
          Structure formulaStructure formula
          Purity≥97% by HPLC
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Toxicity Irritant