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104352 L-Histidine

EMPROVE® EXPERT Ph Eur,ChP,JP,USP

L-Histidine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: His

CAS #: 71-00-1 EC Number: 200-745-3 Molar Mass: 155.15 g/mol Hill Formula: C₆H₉N₃O₂ Grade: Ph Eur,ChP,JP,USP
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104352
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주요 사양표

CAS #EC NumberHill FormulaMolar MassGrade Value
71-00-1200-745-3C₆H₉N₃O₂155.15 g/molPh Eur,ChP,JP,USP

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              		 Plastic bottle 1 kg
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                  Description
                  Catalogue Number104352
                  SynonymsHis
                  References
                  Product Information
                  CAS number71-00-1
                  EC number200-745-3
                  GradePh Eur,ChP,JP,USP
                  Hill FormulaC₆H₉N₃O₂
                  Molar Mass155.15 g/mol
                  HS Code2933 29 92
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Density1.449 g/cm3 (20 °C)
                  Melting Point285 °C (decomposition)
                  pH value7.0 - 8 (15.5 g/l, H₂O, 25 °C)
                  Bulk density430 kg/m3
                  Solubility38.2 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat > 5110 mg/kg
                  Safety Information according to GHS
                  RTECSMS3070000
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at +2°C to +30°C.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications
                  Assay (acidimetric, calculated on dried substance)98.5 - 101.0 %
                  Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
                  Identity (IR-spectrum)passes test
                  Identity (specific rotation)passes test
                  Identity (TLC)passes test
                  Appearancewhite to almost white fine-crystalline powder or colorless crystals
                  Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₇.
                  Appearance of solution (20 g/l, water)clear and colorless
                  Transmittance of solution (30 g/l, water)≥ 98.0 %
                  Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 120 g/l, calc. on dried substance)+11.4 to +12.4
                  Spec. rotation (α 25/D, 110 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+12.6 to +14.0
                  Spec. rotation (α 20/D, 110 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+12.0 to +12.8
                  pH (20 g/l, CO₂-free water)7.0 - 8.5
                  Acidity (20g/l, water)7.0 - 8.5
                  Chloride (Cl)≤ 200 ppm
                  Sulfate (SO₄)≤ 200 ppm
                  Heavy metals (as Pb)≤ 10 ppm
                  As (Arsenic)≤ 1 ppm
                  Cu(Copper)≤ 25 ppm
                  Fe (Iron)≤ 10 ppm
                  Mn (Manganese)≤ 25 ppm
                  Zn (Zinc)≤ 130 ppm
                  Other amino acids (TLC)≤ 0.5 %
                  Related Compounds, total (TLC)≤ 0.5 %
                  Related substances (TLC)passes test
                  Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
                  Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
                  Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
                  Residual solvents (ICH (Q3C))excluded by manufacturing process
                  Sulfated ash (600 °C)≤ 0.1 %
                  Loss on drying (105 °C; 3 h)≤ 0.2 %
                  Bacterial endotoxins< 2.0
                  Bacterial endotoxins (ChP)< 6.0
                  Microbiological test (total aerobic microbial count (TAMC))≤ 10²
                  Microbiological test (total yeast and mould count (TYMC))≤ 10²
                  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                  Corresponds to Ph. Eur., ChP, JP, USP
                  Global Trade Item Number
                  카탈로그 번호 GTIN
                  1.04352.0001 04027269365486
                  1.04352.0500 04027269365042
                  1.04352.1000 04022536906829
                  1.04352.9010 04022536906836

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  10.1

                  Quality Management Dossier (Open Access)

                  Title

                  Operational Excellence Dossier

                  Title

                  L-Histidine MSDS

                  타이틀

                  물질안전보건자료(MSDS) 

                  L-Histidine Certificates of Analysis

                  제품 번호 패킹스펙로트(lot) 번호
                  1.04352.0001 Plastic bottlePDF 사양 문건
                  1.04352.0500 Plastic bottlePDF 사양 문건
                  1.04352.1000 Plastic bottlePDF 사양 문건
                  1.04352.9010 Plastic drumPDF 사양 문건

                  Certificates

                  Title

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                  관련 제품: Brand Facete

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                  카테고리

                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Ingredients - Liquid
                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Ingredients - Liquid
                  Biopharmaceutical Manufacturing > Upstream Processing > Cell Culture > Cell Culture Ingredients and Supplements > Cell Culture Ingredients > Amino Acids
                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Surfactants and Stabilizers
                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers
                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Surfactants and Stabilizers