3301
17β-Estradiol
≥97% (HPLC), solid, estrogenic hormone, Calbiochem
동의어(들):
17β-Estradiol, 17 beta Estradiol
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C18H24O2
CAS 번호:
Molecular Weight:
272.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (by assay)
Form:
solid
Storage condition:
OK to freeze
제품 이름
17β-Estradiol, Most potent mammalian estrogenic hormone.
Quality Segment
description
RTECS - KG2975000
Merck USA index - 14, 3703
assay
≥97% (by assay)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
solubility
ethanol: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
O[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)O)CC3)CC1)C
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
General description
17β-Estradiol is a potent estrogen, a steroid hormone, involved in reproductive and endocrine functions in mammals. It binds to estrogen receptors (ERα and ERβ) to regulate gene expression, influencing reproductive functions such as the proliferation of the uterine endometrium, ovulation, and maintenance of pregnancy. Additionally, 17β-Estradiol is involved in modulating metabolic processes, including lipid metabolism and insulin sensitivity, and exerts neuroprotective effects in the central nervous system.
Application
17β-Estradiol has been used to treat primary rat cortical neurons, to investigate its effects on neuronal responses to interleukin (IL)-6 and soluble IL-6 receptor treatment. It has also been administered subcutaneously to ovariectomized female mice to investigate its effects on Crhr1 and Esr1 mRNA expression in the nucleus accumbens.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
signalword
Danger
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - ED ENV 1 - ED HH 1 - Lact. - Repr. 1A