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Merck

FCMAB418PE-I

Milli-Mark® Anti-CAR-PE Antibody, clone RmcB

clone RmcB, Milli-Mark®, from mouse

동의어(들):

46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3 binding protein, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, coxsackie virus B receptor, coxsackie virus and adenovirus receptor

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
PE
Clone:
RmcB, monoclonal
Application:
FACS
Citations:
2
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biological source

mouse

Quality Segment

conjugate

PE

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RmcB, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CXADR(1525)

General description

The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR′s biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation.
40 kDa Calculated. Uniprot indicates multiple isoforms ranging from 9 to 40 kDa

Immunogen

Native human coxsackie virus-adenovirus receptor protein

Application

Detect CAR using this Milli-Mark Anti-CAR-PE Antibody, clone RmcB validated for use in FC.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Biochem/physiol Actions

Antibody recognizes CAR.

Physical form

Protein G Purified
Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
HT-29 cells
Evaluated by flow cytometry using HT-29 cells.

Other Notes

Unconjugated version Cat. No. 05-644 is known to react with Mouse and Rat.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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