106425 N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem

106425
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      개요

      Replacement Information

      주요 사양표

      Empirical FormulaCAS #
      C₅H₉NO₃S 616-91-1

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      106425-5GMCN
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          Plastic ampoule 5 gm
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          Description
          OverviewMucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
          Catalogue Number106425
          Brand Family Calbiochem®
          SynonymsLNAC
          References
          ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
          Product Information
          CAS number616-91-1
          FormWhite solid
          Hill FormulaC₅H₉NO₃S
          Chemical formulaC₅H₉NO₃S
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥98% by titration
          Physicochemical Information
          ContaminantsFe: ≤20 ppm
          Cl: ≤ 0.04%
          Sulfate: ≤ 0.03%
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSHA1660000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          106425

          References

          참고문헌 보기
          Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure

          Citations

          타이틀
        • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-May-2017 JSW
          SynonymsLNAC
          DescriptionA mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number616-91-1
          RTECSHA1660000
          Chemical formulaC₅H₉NO₃S
          Structure formulaStructure formula
          Purity≥98% by titration
          ContaminantsFe: ≤20 ppm
          Cl: ≤ 0.04%
          Sulfate: ≤ 0.03%
          SolubilityH₂O (50 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 88
          ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
          Citation
        • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.