116805 PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem

116805
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      가격 및 재고 조회

      개요

      Replacement Information

      주요 사양표

      Empirical FormulaCAS #
      C₉₄H₁₄₈N₃₂O₃₁ 99534-03-9

      가격 및 재고여부

      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      116805-500UGCN
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          Plastic ampoule 500 μg
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          Description
          OverviewA potent synthetic peptide that is a competitive inhibitor of protein kinase A (Ki = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. Binds to the catalytic subunit of PKA and displaces the regulatory subunit. Mimics the protein substrate by binding to the catalytic site via the arginine-cluster basic substrate.
          Catalogue Number116805
          Brand Family Calbiochem®
          SynonymsProtein Kinase A Inhibitor 5-24, H-TTYADFIASGRTGRRNAIHD, PKA Inhibitor IV
          References
          ReferencesKnighton, D.R., et al. 1991. Science 253, 525.
          Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989.
          Rusine, T., et al. 1986. J. Cell Biol. 102, 1630.
          Wong, Y.S., et al. 1986. J. Biol. Chem. 12089.
          Product Information
          CAS number99534-03-9
          ATP CompetitiveN
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
          Hill FormulaC₉₄H₁₄₈N₃₂O₃₁
          Chemical formulaC₉₄H₁₄₈N₃₂O₃₁
          Hygroscopic Hygroscopic
          ReversibleN
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetPKA
          Primary Target K<sub>i</sub>2.3 nM for protein kinase A
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem Certificates of Analysis

          TitleLot Number
          116805

          References

          참고문헌 보기
          Knighton, D.R., et al. 1991. Science 253, 525.
          Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989.
          Rusine, T., et al. 1986. J. Cell Biol. 102, 1630.
          Wong, Y.S., et al. 1986. J. Biol. Chem. 12089.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          SynonymsProtein Kinase A Inhibitor 5-24, H-TTYADFIASGRTGRRNAIHD, PKA Inhibitor IV
          DescriptionPeptide corresponding to the active site on the skeletal muscle inhibitor protein. Competitive inhibitor of protein kinase A (Ki = 2.3 nM).
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
          CAS number99534-03-9
          Chemical formulaC₉₄H₁₄₈N₃₂O₃₁
          Peptide SequenceH-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
          Purity≥95% by HPLC
          SolubilityH₂O (1 mg/ml). Sonication or the addition of a few drops of dilute acid (10 mM HCl) may be necessary to achieve complete solubilization.
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Toxicity Standard Handling
          ReferencesKnighton, D.R., et al. 1991. Science 253, 525.
          Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989.
          Rusine, T., et al. 1986. J. Cell Biol. 102, 1630.
          Wong, Y.S., et al. 1986. J. Biol. Chem. 12089.