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Merck

1.52021

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 50 mm x 4.6 mm HPLC Column

동의어(들):

Chromolith® HighResolution RP-18 endcapped 50-4.6 HPLC column

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
41115709
NACRES:
SB.52
Matrix active group:
C18 bonding phase, octadecylsilane (ODS), C18 bonding phase
Pore size:
1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity
Matrix:
highly porous, monolithic silica
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제품 이름

Chromolith® HighResolution RP-18 endcapped, L × I.D. 50 mm x 4.6 mm HPLC column

material

PEEK column

Quality Level

agency

suitable for USP L1

product line

Chromolith®

feature

endcapped

packaging

1 ea of

extent of labeling

15% Carbon loading, 18% Carbon loading

parameter

50 °C max. temp., 200 bar pressure, 45 °C max. temp.

technique(s)

HPLC: suitable, LC/MS: suitable, mass spectrometry (MS): suitable (High)

column L × I.D.

5 cm × 4.6 mm

matrix

highly porous, monolithic silica

matrix active group

C18 bonding phase, octadecylsilane (ODS), C18 bonding phase

pore size

1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity

operating pH range

2-7.5

separation technique

reversed phase

storage temp.

no temp limit

General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping.

Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column. Chromolith® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications.
The column dimension of 50 mm length and 4.6 mm I.D. is the best choice for very fast separations on any HPLC System and rapid method devlopment.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces) [1.52025] with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]

The Chromolith® column coupler can be used to significantly increase the separation efficiency of Chromolith® columns by coupling several columns in series (up to 100,000 plates/per column).
[151467]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Chromolith® HighResolution RP-18 endcapped columns are also available in 2 mm I.D. column dimension for perfect fit to UHPLC and UHPLC-MS needs.
Flyer: [UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns]

Analysis Note

Pressure: 15 - 50 bar
Performance (anthracene)
Theoretical Plates (N/m) (Anthracene): ≥ 135000
Capacity factor (Anthracene): 3.2 - 4.2
Tailing (USP): 0.90 - 1.35 %
Selectivity
separation factor (anthracene/progesterone): 1.90 - 2.35

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany


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문서

Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.





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SKUGTIN
1.52021.000104027269204839