Skip to Content
Merck

Key Documents

View All Documentation

5.04523

CP-101,606

Synonym(s):

CP-101,606, Traxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C20H25NO3
CAS Number:
134234-12-1
Molecular Weight:
327.42
UNSPSC Code:
12352200
MDL number:
MFCD00926469
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
OK to freeze, protect from light
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98% (HPLC)

Quality Segment

100

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 35 mg/mL

storage temp.

2-8°C

InChI

1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1

InChI key

QEMSVZNTSXPFJA-HNAYVOBHSA-N

General description

A highly selective antagonist for NR2B subunit containing NMDA receptors (IC50 = 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.

Biochem/physiol Actions

Primary Target
NMDA receptors
Target IC50: 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Taniguchi, K., et al. 2009. British J. Pharmacol.122, 809.
Menniti, F., et al. 1997. Eur. J. Pharmacol.331, 117.

Nicholson, K., et al. 2007. Behavioural Pharmacology18, 731.
Bullock, M., et al. 2006. Annals of the New York Academy of Sciences890, 51.

Preskorn, S., et al. 2008. J. Clin. Psychopharmacol.28, 631.

Yurkewicz, L., et al. 2005. J. Neurotrauma.22, 1428.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Still not finding the right product?

Explore all of our products under CP-101,606

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library