MABE1033
Anti-SMARCB1 Antibody, clone 2C2
clone 2C2, from mouse
동의어(들):
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, BRG1-associated factor 47, BAF47, Integrase interactor 1 protein, SNF5 homolog, hSNF5, SMARCB1
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제품정보 (DICE 배송 시 비용 별도)
eCl@ss:
32160702
UNSPSC Code:
12352203
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2C2, monoclonal
species reactivity
human
technique(s)
immunocytochemistry: suitable, western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SMARCB1(6598)
General description
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1), also known as BRG1-associated factor 47 (BAF47) or Integrase interactor 1 protein or SNF5 homolog (hSNF5), and encoded by the gene name SMARCB1 or BAF47, is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein has also been shown to bind to and enhance the DNA joining activity of HIV-1 integrase. It has been found to be a tumor suppressor, and the loss of SMARCB1 has been associated with malignant rhabdoid tumors. Tumor cells of synovial sarcoma seem to have a post transcriptional regulatory mechanism for SMARCB1.
~ 45 kDa observed
Immunogen
GST-tagged recombinant protein corresponding to human SMARCB1.
Application
Anti-SMARCB1 Antibody, clone 2C2 is an antibody against SMARCB1 for use in Western Blotting and Immunocytochemistry.
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected SMARCB1 in 10 µg of HEK293 cell lysate.
Immunocytochemistry Analysis: A representative lot detected SMARCB1 in HeLa cells (Harada, A., et al. (2014). Mono. Antibodies in Immuno. and Immunotherapy. 33:49-51).
Western Blotting Analysis: A representative lot detected SMARCB1 in HeLa cells (Harada, A., et al. (2014). Mono. Antibodies in Immuno. and Immunotherapy. 33:49-51).
Immunocytochemistry Analysis: A representative lot detected SMARCB1 in HeLa cells (Harada, A., et al. (2014). Mono. Antibodies in Immuno. and Immunotherapy. 33:49-51).
Western Blotting Analysis: A representative lot detected SMARCB1 in HeLa cells (Harada, A., et al. (2014). Mono. Antibodies in Immuno. and Immunotherapy. 33:49-51).
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SMARCB1 in 10 µg of HeLa cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SMARCB1 in 10 µg of HeLa cell lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable