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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C20H10N2Na2O4 · xH2O
CAS 번호:
Molecular Weight:
388.28 (anhydrous basis)
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
제품 이름
Bicinchoninic acid disodium salt hydrate, ≥98% (HPLC)
SMILES string
O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3
InChI
1S/C20H12N2O4.2Na.H2O/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;;/h1-10H,(H,23,24)(H,25,26);;;1H2/q;2*+1;/p-2
InChI key
FAFVGCAYKZKOPT-UHFFFAOYSA-L
assay
≥98% (HPLC)
form
powder
technique(s)
titration: suitable
color
white to light yellow
solubility
0.5% sodium bicarbonate: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
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Application
- Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.
- It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose).
- It has been used for determining protein concentration.
Biochem/physiol Actions
Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.
Teng F, et al.
Experimental Neurology, 248, 416-428 (2013)
Detection and characterization of chitinases and other chitin-modifying enzymes.
Howard MB, et al.
Journal of Industrial Microbiology & Biotechnology, 30, 627-635 (2003)
Ramya Kumareswaran et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 116(3), 388-391 (2015-04-07)
Solid tumors contain regions of chronic and cyclic hypoxia. Chronic hypoxia can downregulate RAD51 and sensitize cells to PARP inhibition. Herein, we show that RAD51 expression, cell survival and toxicity to PARP inhibition is not affected under cyclic hypoxic conditions.
Rajeev Kumar et al.
Bioresource technology, 130, 372-381 (2013-01-15)
Two established delignification methods employing sodium chlorite-acetic acid (SC/AA) and peracetic acid (PAA) are often used, and are reportedly highly selective. However, these reports are mostly for highly recalcitrant and unpretreated softwoods and hardwoods species, and information for less recalcitrant
Makon-Sébastien Njock et al.
Blood, 125(20), 3202-3212 (2015-04-04)
The blood contains high concentrations of circulating extracellular vesicles (EVs), and their levels and contents are altered in several disease states, including cardiovascular disease. However, the function of circulating EVs, especially the microRNAs (miRNAs) that they contain, are poorly understood.
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