D3447
Doxycycline hydrochloride
동의어(들):
2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6R,12aS)-
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C22H24N2O8 · HCl
CAS 번호:
Molecular Weight:
480.90
MDL number:
UNSPSC Code:
51284028
NACRES:
NA.85
Quality Level
biological source
synthetic
form
powder
color
yellow
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycoplasma, parasites
mode of action
protein synthesis | interferes
storage temp.
−20°C
InChI
1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1H/b21-13-;/t7-,10+,14+,15-,17-,22-;/m0./s1
InChI key
VLUQVUWDECWBTL-UQVCFKGQSA-N
General description
Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo.
Application
Doxycycline hydrochloride has been used for the induction of shRNA expression and induction of expression vectors.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
John D Chan et al.
Nature communications, 8(1), 1910-1910 (2017-12-07)
Schistosomiasis is a debilitating tropical disease caused by infection with parasitic blood flukes. Approximately 260 million people are infected worldwide, underscoring the clinical and socioeconomic impact of this chronic infection. Schistosomiasis is treated with the drug praziquantel (PZQ), which has
David van Dijk et al.
Cell, 174(3), 716-729 (2018-07-03)
Single-cell RNA sequencing technologies suffer from many sources of technical noise, including under-sampling of mRNA molecules, often termed "dropout," which can severely obscure important gene-gene relationships. To address this, we developed MAGIC (Markov affinity-based graph imputation of cells), a method that
Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress
Beate H et al.
BMC Cancer (2018)
RNA-seq analysis of impact of PNN on gene expression and alternative splicing in corneal epithelial cells
Debra A et al.
Molecular Vision, 22(40) (2016)
C3 transferase gene therapy for continuous conditional RhoA inhibition
Claire-Anne G et al.
Neuroscience, 339 (2016)
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