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Merck

E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

동의어(들):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS 번호:
Molecular Weight:
292.24
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
39030907
UNSPSC Code:
12161700
EC Number:
200-449-4
MDL number:
Beilstein/REAXYS Number:
1716295
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제품 이름

Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

grade

anhydrous

product line

BioReagent

assay

≥98.5%

form

crystalline

reaction suitability

reagent type: chelator

technique(s)

cell culture | mammalian: suitable

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

solubility

3  M NaOH: 100 mg/mL

density

1.46 g/cm3 at 20 °C

cation traces

C: 40.7-41.5%
N: 9.3-9.8%

Quality Level

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Application

Ethylenediaminetetraacetic acid has been used:
  • as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
  • as a medium component in the hepatic stellate cell (HSCs) culture
  • as a component of homogenization buffer for protein extraction from eye tissues
  • for stopping benzonase reaction in lysis buffer

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Analysis of Direct Interaction between Viral DNA-binding Proteins by Protein Pull-down Co-immunoprecipitation Assay
Lechuga A, et al.
Bio-protocol, 8(1), 1571-1571 (2018)
Intracellular BH3 Profiling Reveals Shifts in Antiapoptotic Dependency in Human B Cell Maturation and Mitogen-Stimulated Proliferation
Dai J and Luftig MA
Journal of Immunology, ji1701473-ji1701473 (2018)
Protein Expressions of the Small GTPase Rho Proteins in Pterygial Tissue and Leukocytes of Patients with Pterygium
Saracaloglu A, et al.
Proceedings, 2(25), 1571-1571 (2018)
The blockade of lipophagy pathway is necessary for docosahexaenoic acid to regulate lipid droplet turnover in hepatic stellate cells
Qiu S, et al.
Biomedicine and Pharmacotherapy, 109, 1841-1850 (2019)
Does calcium disodium EDTA slow CKD progression?
Weaver VM, et al.
American Journal of Kidney Diseases, 60(4), 503-506 (2012)

프로토콜

TE Buffer; Elution Buffer; 10x Ligation Buffer; 0.5 M PIPES Buffer; Inoue Transformation Buffer

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