S5545
Anti-Serotonin antibody produced in rabbit
whole antiserum
동의어(들):
Anti-Serotonin, Rabbit Anti-Serotonin, Serotonin Detection Antibody
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (f), IHC (p)
Citations:
276
biological source
rabbit
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
species reactivity
rat, human
packaging
antibody small pack of 25 μL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:8,000 using sections of normal human appendix or serotonin-containing carcinoid tumors, immunohistochemistry (frozen sections): 1:5,000 using perfusion-fixed (4% paraformaldehyde), frozen sections of rat brain.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HTR1A(3350)
General description
Serotonin/5-HT (5-hydroxytryptamine) is a neurotransmitters present in the brain. Anti-Serotonin specifically stains enterochromaffin cells in formalin-fixed, paraffin-embedded sections of normal human appendix and serotonin-containing carcinoid tumors. In the central nervous system (CNS), the antiserum reacts with serotonin-containing fibers in perfusion-fixed, free-floating sections of rat brain.
Immunogen
Serotonin creatinine sulfate complex conjugated with formaldehyde to BSA.
Application
Anti-Serotonin antibody has been used in immunocytochemistry.
Biochem/physiol Actions
Serotonin/5-HT, the midbrain raphe system controls mood, emotion, cognition and motor functions, circadian and neuroendocrine rhythms, like food intake, sleep and reproductive activity. It participates in natural reward-related physiology and behaviour, from feeding to sexual activity.
The antibody reacts with serotonin-containing fibers in paraformaldehyde perfusion-fixed, frozen sections of rat brain. The product specifically stains enterochromaffin cells in formalin-fixed, paraffin embedded sections of normal human appendix and serotonin-containing carcinoid tumors.
Physical form
Supplied as a liquid containing 15 mM sodium azide as preservative.
Preparation Note
For continuous use, store at 2-8 °C for a maximum of one month. For extended storage freeze in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Roles for serotonin in neuroembryogenesis.
Bernard H, et al.
Serotonin, 477-506 (1981)
Martin Fritsch et al.
Frontiers in zoology, 10(1), 35-35 (2013-06-20)
One of the most interesting riddles within crustaceans is the origin of Cladocera (water fleas). Cladocerans are morphologically diverse and in terms of size and body segmentation differ considerably from other branchiopod taxa (Anostraca, Notostraca, Laevicaudata, Spinicaudata and Cyclestherida). In
Allelic Variation of Human Serotonin Transporter Gene Expression
Armin H, et al.
Journal of Neurochemistry, 66(6), 2621-2624 (1996)
Characterization of efferent projections of chemosensitive neurons in the caudal parapyramidal area of the rat brain
Ribas-Salgueiro JL, et al.
Brain Research Bulletin, 66(3), 235-248 (2005)
Caroline B Palavicino-Maggio et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(34), 17029-17038 (2019-08-09)
In the Drosophila model of aggression, males and females fight in same-sex pairings, but a wide disparity exists in the levels of aggression displayed by the 2 sexes. A screen of Drosophila Flylight Gal4 lines by driving expression of the
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Datasheet
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