Millipore Sigma Vibrant Logo
 

Racing with Revolutionary Technology

Request Information

The high-purity silica of Chromolith® monolithic HPLC columnsChromolith® monolithic HPLC columns combine speed and efficiency like never before. They are not packed with small silica particles like conventional HPLC columns. Instead, each Chromolith® column consists of a single rod of high-purity polymeric silica gel with a bimodal pore structure of macro and mesopores. The macropores reduce column back pressure, allowing significantly faster flow rates. The mesopores form a fine porous structure, which creates a very large active surface area for high-efficiency separations. For even greater efficiency, multiple Chromolith® columns can be coupled to achieve a higher theoretical plate count with still very low back pressure.

Features and Benefits

  • High throughput at high flow rates
  • Possibility of flow gradients
  • Improved security, robustness, reliability and versatility
  • Column length no longer pressure limited
  • Cost savings due to increased sample throughput
  • Added performance by column coupling
  • Significantly longer column lifetime

Relief from Back Pressure

Conventional HPLC columns often suffer from high back pressure. This reduces column lifetime, system robustness, and the operational range of flow rates. These columns are also limited in length, and in their number of theoretical plates. Moreover, increasing plate count by decreasing particle size further raises back pressure, and restricts the variety of separations possible. To truly accelerate the process, there’s no better choice than Chromolith® HPLC columns. Their unique monolithic silica technology minimizes back pressure while maximizing speed, robustness and selectivity.

Different Lengths to Suit Your Application

  • Chromolith® Flash, 25 mm length: For ultra-fast separation of simple mixtures
  • Chromolith® SpeedROD, 50 mm length: For fast separation of simple mixtures
  • Chromolith® Performance, 100 mm length: For rapid separation of more complex mixtures

Validation Kit

The Chromolith® validation kit includes three columns from three different production batches, allowing you to easily compare batch-to-batch reproducibility and quality. This makes the validation kit an ideal tool for quality control and validation laboratories.

Chromolith® HighResolution

Whereas standard Chromolith® columns have 2 μm macropores, Chromolith® HighResolution columns possess 1.15 μm macropores. This results in higher efficiency, and improved peak shape. Although this causes higher back pressure, it is still less than half that of any particulate column of the same dimensions.

 
 
 
크로마토그래피
어플리케이션 노트 파인더
분석물, 컬럼 종류, 검출 방법, 흡착제 타입 또는 다양한 검색어를 이용하여 크로마토그래피 어플리케이션을 검색할 수 있습니다:
 
HPLC 작업흐름 솔루션 - 고정상

HPLC 작업흐름 솔루션

고정상

더 보기

분석 어플리케이션 월드

크로마토그래피 어플리케이션 월드

The ultimate source for the latest news in your field

무엇이 새로운지 확인하십시오.
Chromolith® WidePore 300 HPLC Columns

Video

Chromolith® WidePore 300 HPLC Columns

Watch Video
 

이벤트

6월 30
06/30/20
Spotlight eLearning Series
Virtual
Virtual
Analytics and Sample Preparation 유럽 20200630
11월 10
11/10/20 - 11/12/20
BrauBeviale
Nürnberg Exhibition Centre
Nuremberg, Germany
Water Purification,Reagents Chemicals and Labware,Industrial Biomonitoring,Analytics and Sample Preparation 유럽 20201110