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Merck

S9763

Sodium phosphate dibasic

ACS reagent, ≥99.0%

Synonym(s):

sec-Sodium phosphate, Disodium hydrogen phosphate, Disodium phosphate, Sodium hydrogenphosphate

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About This Item

Linear Formula:
Na2HPO4
CAS Number:
7558-79-4
Molecular Weight:
141.96
PubChem Substance ID:
329824633
eCl@ss:
38070211
UNSPSC Code:
12352302
NACRES:
NA.21
EC Number:
231-448-7
MDL number:
MFCD00003496

Product Name

Sodium phosphate dibasic, ACS reagent, ≥99.0%

InChI key

BNIILDVGGAEEIG-UHFFFAOYSA-L

InChI

1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

SMILES string

[Na+].[Na+].[H]OP([O-])([O-])=O

grade

ACS reagent

agency

suitable for SM 5210

assay

≥99.0%

form

powder

impurities

≤0.002% Chloride (Cl)
≤0.01% Insoluble matter

loss

≤0.2% loss on drying, 105°C

pH

8.7-9.3 (25 °C, 5% in solution)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

solubility

water: 5% at 25 °C, clear

anion traces

sulfate (SO42-): ≤0.005%

cation traces

Fe: ≤0.002%
heavy metals: ≤0.001% (by ICP-OES)

Quality Level

200

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Application

Sodium phosphate dibasic has been used in:
  • the preparation of phosphate buffer saline solution for perfusion procedure
  • western blot
  • indirect enzyme linked immunosorbent assay

General description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Other Notes

Go to Redi-Dri™ Product Listing 795410

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000515297
0000515297
0000468889
0000468889
0000503541

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Response of Rainbow Trout (Oncorhynchus mykiss) Growing from 50 to 200 g to Supplements of Dibasic Sodium Phosphate in a Semipurified Diet
Rodehutscord M
The Journal of Nutrition (1996)
Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats
Tsuchiya N, et al.
Toxicologic Pathology, 408-412 (2004)
Premixed tricalcium silicate/sodium phosphate dibasic cements for root canal filling
Wu Meng, et al.
Materials Chemistry and Physics (2021)
Karsten Krug et al.
Cell, 183(5), 1436-1456 (2020-11-20)
The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this "proteogenomics" approach was applied to 122 treatment-naive primary breast cancers accrued to preserve post-translational modifications, including protein phosphorylation and acetylation. Proteogenomics challenged
Michael A Gillette et al.
Cell, 182(1), 200-225 (2020-07-11)
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale proteomics, phosphoproteomics, and acetylproteomics. Multi-omics clustering revealed four
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