Millipore Sigma Vibrant Logo

126850 α₁-PDX, Human, Recombinant, E. coli - Calbiochem

126850
Voir les Prix & la Disponibilité

Aperçu

Replacement Information

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
126850-2.5MG
Récupération des données relatives à la disponibilité...
Disponibilité limitéeDisponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      Ampoule plast. 2.5 mg
      Prix en cours de récupération
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      Demander le prix
      Description
      OverviewRecombinant protein derived from the bioengineered human α1-antitrypsin gene fused to a His•Tag® sequence and a FLAG®-tag. Contains a minimal furin consensus sequence, RXXR, that effectively blocks the furin-dependent processing of protein precursors (Ki = 600 pM). Extracellular application of α1-PDX can be used to inhibit the processing of biologically significant proteins including viral envelope glycoproteins, bacterial toxins, receptors, and growth factors. Useful for in vivo and in vitro furin inhibition assays.
      Catalogue Number126850
      Brand Family Calbiochem®
      Synonymsα₁-Antitrypsin Portland
      References
      ReferencesBassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Jean, F., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 2864.
      Jean, F., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 7293.
      Product Information
      ATP CompetitiveN
      FormLyophilized solid
      FormulationLyophilized from PBS.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFurin-dependent processing of protein precursors
      Primary Target K<sub>i</sub>600 pM against furin-dependent processing of protein precursors
      Purity≥80% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      α₁-PDX, Human, Recombinant, E. coli - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      126850

      Références bibliographiques

      Aperçu de la référence bibliographique
      Bassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Jean, F., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 2864.
      Jean, F., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 7293.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2008 JSW
      Synonymsα₁-Antitrypsin Portland
      DescriptionRecombinant protein derived from the bioengineered human α1-antitrypsin gene fused to a His·Tag® and a FLAG·Tag. Contains a minimal furin consensus sequence, RXXR, that effectively blocks the furin-dependent processing of protein precursors (Ki = 600 pM). α1-PDX can be used in extracellular applications to block the processing of furin substrates. α1-PDX has been shown to inhibit the processing of biologically significant proteins including viral envelope glycoproteins, bacterial toxins, receptors, and growth factors.
      FormLyophilized solid
      FormulationLyophilized from PBS.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥80% by SDS-PAGE
      SolubilityH₂O (2.5 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Yes
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBassi, D.E., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 10326.
      Jean, F., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 2864.
      Jean, F., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 7293.