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505019 (2S,4R)-4-methylglutamate - CAS 31137-74-3 - Calbiochem

505019
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Empirical FormulaCAS #
C₆H₁₁NO₄ 31137-74-3

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      Description
      OverviewA potent agonist highly selective for kainate receptors over AMPA receptors (EC50 = 0.06-0.38 µM and 132-453 µM for kainate and AMPA receptors, respectively). Useful for distinguishing the functional roles played by kainate and AMPA receptors in neurotransmissions.
      Catalogue Number505019
      Brand Family Calbiochem®
      SynonymsKainate Receptor Agonsit, (2S,4R)-4-methylglutamate, SYM 2081
      References
      ReferencesTurner, S., et al. 2003. Brain Res. 973, 252.
      Ta, E., et al. 2000. J. Peri. Nerv. Sys. 5, 123.
      Donevan, D., et al. 1998. J. Pharmacol. & Exp. Therap. 285, 539.
      Zhou, M., et al. 1997. J. Pharmacol. & Exp. Therap. 280, 422.
      Product Information
      CAS number31137-74-3
      FormWhite powder
      Hill FormulaC₆H₁₁NO₄
      Chemical formulaC₆H₁₁NO₄
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary Targetkainate receptors
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      (2S,4R)-4-methylglutamate - CAS 31137-74-3 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Turner, S., et al. 2003. Brain Res. 973, 252.
      Ta, E., et al. 2000. J. Peri. Nerv. Sys. 5, 123.
      Donevan, D., et al. 1998. J. Pharmacol. & Exp. Therap. 285, 539.
      Zhou, M., et al. 1997. J. Pharmacol. & Exp. Therap. 280, 422.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      SynonymsKainate Receptor Agonsit, (2S,4R)-4-methylglutamate, SYM 2081
      DescriptionA potent agonist highly selective for kainate receptors over AMPA receptors (EC50 = 0.06-0.38 µM and 132-453 µM for kainate and AMPA receptors, respectively). Useful for distinguishing the functional roles played by kainate and AMPA receptors in neurotransmissions.
      FormWhite powder
      CAS number31137-74-3
      Chemical formulaC₆H₁₁NO₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (10 mg/ml)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTurner, S., et al. 2003. Brain Res. 973, 252.
      Ta, E., et al. 2000. J. Peri. Nerv. Sys. 5, 123.
      Donevan, D., et al. 1998. J. Pharmacol. & Exp. Therap. 285, 539.
      Zhou, M., et al. 1997. J. Pharmacol. & Exp. Therap. 280, 422.