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164606 Aminopeptidase N/CD13 Inhibitor - Calbiochem

164606
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Tableau de caractéristiques principal

Empirical Formula
C₁₃H₂₂NO₃P

Prix & Disponibilité

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164606-10MG
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      Description
      OverviewAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
      Catalogue Number164606
      Brand Family Calbiochem®
      Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
      References
      ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
      Product Information
      FormWhite solid
      Hill FormulaC₁₃H₂₂NO₃P
      Chemical formulaC₁₃H₂₂NO₃P
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Aminopeptidase N/CD13 Inhibitor - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Aminopeptidase N/CD13 Inhibitor - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      164606

      Références bibliographiques

      Aperçu de la référence bibliographique
      Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-April-2012 JSW
      Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
      DescriptionAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
      FormWhite solid
      Chemical formulaC₁₃H₂₂NO₃P
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Solubility0.1N NaOH (1 mg/ml). Only partially soluble at 1 mg/ml in DMSO or H₂O.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.