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520219 PPACK II, Trifluoroacetate Salt - CAS 74392-49-7 - Calbiochem

520219
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Empirical FormulaCAS #
C₂₅H₃₃ClN₆O₃ . 2CF₃COOH 74392-49-7

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520219-10MG
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      Ampoule plast. 10 mg
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      Description
      OverviewPotent and specific irreversible inhibitor of plasma and glandular kallikreins. Also available as a 10 mM solution in H2O (Cat. No. 508573).
      Catalogue Number520219
      Brand Family Calbiochem®
      References
      ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Product Information
      CAS number74392-49-7
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
      Chemical formulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationPPACK II, Trifluoroacetate Salt, CAS 74392-49-7, is a potent, specific, and irreversible inhibitor of plasma and glandular kallikreins.
      Biological Information
      Primary TargetPlasma and glandular kallikreins
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      PPACK II, Trifluoroacetate Salt - CAS 74392-49-7 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      520219

      Références bibliographiques

      Aperçu de la référence bibliographique
      Byrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-October-2013 JSW
      DescriptionPotent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.
      FormOff-white solid
      CAS number74392-49-7
      Chemical formulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
      Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
      Purity≥95% by HPLC
      SolubilityH₂O (100 mg/ml)
      Storage +2°C to +8°C
      Protect from moisture
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Standard Handling
      ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.