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3050-OP

CHAPS

OmniPur® Grade

Sinónimos:

CHAPS, 3-[(3-Cholamidopropyl)-dimethylammino]-propane- sulfonate, 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

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Fórmula empírica (notación de Hill):
C32H58N2O7S
Número CAS:
75621-03-3
Peso molecular:
614.88
NACRES:
NA.25
UNSPSC Code:
12161703
MDL number:
MFCD00012116
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Nombre del producto

CHAPS, OmniPur® Grade, Zwitterionic detergent

Quality Segment

200

form

crystalline powder

mol wt

micellar avg mol wt 6150

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

aggregation number

10

color

white

CMC

6 mM (20-25°C)

transition temp

cloud point >100 °C

foreign activity

DNAse, none detected, Protease, none detected, RNAse, none detected

shipped in

ambient

storage temp.

10-30°C

SMILES string

C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

UMCMPZBLKLEWAF-RFCNGIAKSA-N

General description

Zwitterionic detergent ideal for solubilization of membrane proteins, analytical, diagnostic, chromatography, electrophoresis work, and enzymology and immunology applications.
Suitable for Molecular Biology

Conductivity (10%, water): ≤50 µmho
DNase: None detected
Protease: None detected
Purity (TLC): Single spot
RNase: None detected
Solubility: 20% in water, passes test





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application

CHAPS is a nondenaturing zwitterionic detergent for membrane biochemistry.
Useful for solubilizing membrane proteins and breaking protein-protein interactions. CHAPS′ small micellar molecular weight (6,150) and high critical micelle concentration (6-10 mM) allow it to be removed from samples by dialysis. It is also suitable for protein solubilization for isoelectric focusing and two-dimensional electrophoresis. CHAPS is commonly used for non-denaturing (without urea) IEF and has been shown to give excellent resolution of some subcellular preparations and plant proteins. Concentrations between 2-4% (w/v) are typically used in an IEF gel.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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