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Merck

8.19015

Polyethylene glycol

greener alternative

3000, for synthesis

Synonym(s):

Poly(ethylene glycol), Polyethylene glycol 3000, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 3000, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
NACRES:
NA.22
EC Index Number:
500-038-2
UNSPSC Code:
13111021
MDL number:

Product Name

Polyethylene glycol, 3000, for synthesis

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

vapor pressure

<0.1 hPa ( 20 °C)

form

liquid

autoignition temp.

420 °C

potency

28000 mg/kg LD50, oral (Rat)
>20000 mg/kg LD50, skin (Rabbit)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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pH

4-7 (20 °C, 100 g/L in H2O)

mp

55-58 °C

transition temp

flash point 270 °C

density

1.21 g/cm3 at 20 °C

bulk density

400‑500 kg/m3

greener alternative category

storage temp.

2-30°C

Quality Level

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Analysis Note

Hydroxyl value: 34 - 42
Melting range (lower value): ≥ 55 °C
Melting range (upper value): ≤ 59 °C
Average molecular mass: 2700 - 3300
Identity (IR): passes test

Application

Polyethylene glycol 3000 can be used as:
  • A surface-modification agent in the synthesis of monodispersed magnetite colloidal magnetic nanoparticles.
  • A precipitating agent in the crystallization of oligoxyloglucan reducing-end specific cellobiohydrolase (OXG-RCBH) by the hanging-drop vapor diffusion method.
  • A solvent and phase-transfer catalyst (PTC) in the application of aqueous biphasic reactive extraction.
  • An additive in the preparation of polysulfone membrane to study the porometry.

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Polyethylene glycol and solutions of polyethylene glycol as green reaction media
Chen Ji, et al.
Green Chemistry, 7(2) (2005)
Katsuro Yaoi et al.
Acta crystallographica. Section D, Biological crystallography, 59(Pt 10), 1838-1839 (2003-09-23)
A novel xyloglucan-specific exo-beta-glycosidase, oligoxyloglucan reducing-end specific cellobiohydrolase (OXG-RCBH), recognizes the reducing end of oligoxyloglucan and releases two glucosyl residue segments from the main chain. OXG-RCBH was crystallized by the hanging-drop vapour-diffusion method with polyethylene glycol 3000 and polyethylene glycol
Eleftherios Halevas et al.
Journal of inorganic biochemistry, 213, 111271-111271 (2020-10-19)
Targeted tissue drug delivery is a challenge in contemporary nanotechnologically driven therapeutic approaches, with the interplay interactions between nanohost and encapsulated drug shaping the ultimate properties of transport, release and efficacy of the drug at its destination. Prompted by the
Porometry studies of the polysulfone membranes on addition of poly (ethylene glycol) in gelation bath during preparation
Yogesh SJ, et al.
Journal of the Mexican Chemical Society, 52(2) (2008)

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