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852045 Fmoc-Gln(Trt)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
132327-80-1C₃₉H₃₄N₂O₅610.72 g/mol

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      8520450100
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          Description
          Catalogue Number852045
          Replaces04-12-1090
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-N-γ-trityl-L-glutamine
          Background InformationFmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln [1]. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.

          The product number for this product was previously 04-12-1090.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number132327-80-1
          Hill FormulaC₃₉H₃₄N₂O₅
          Molar Mass610.72 g/mol
          HS Code2924 29 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ400
          Applications
          ApplicationFmoc-Gln(Trt)-OH Novabiochem®. CAS 132327-80-1, molar mass 610.72 g/mol.
          Biological Information
          Physicochemical Information
          Melting Point130.5 °C
          pH value5.4 (H₂O, 22.9 °C)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at -10°C to -25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Color (visual)white to off white
          Appearance of substance (visual)powder
          Color index (0,5 M in DMF)≤ 160 Hazen
          Identity (IR)passes test
          Enantiomeric purity≥ 99.8 % (a/a)
          Purity (HPLC)≥ 99.0 % (a/a)
          Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-ß-Ala-Gln (Trt) -OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-Gln(Trt)-Gln(Trt)-OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-Gln-OH (HPLC)≤ 0.1 % (a/a)
          Assay free amino acid (GC)≤ 0.2 %
          Purity (TLC(011A))≥ 98 %
          Purity (TLC(0811))≥ 98 %
          Solubility (25 mmole in 50 ml DMF)clearly soluble
          Assay (acidimetric)≥ 93.0 %
          Water (K. F.)≤ 2.0 %
          Ethyl acetate (HS-GC)≤ 0.5 %
          Acetate (IC)≤ 0.02 %
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8520450025 04027269086954
          8520450100 04027269086961

          Documentation

          Fmoc-Gln(Trt)-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          [1] P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739.