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573115 SMCC, Water-Soluble

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573115
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Descripción

Replacement Information

Tabla espec. clave

CAS #Purity
92921-24-9≥94% by HPLC

Precios y disponibilidad

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573115-50MG
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      Description
      OverviewIdeal for coupling enzymes to antibodies. Contains a cyclohexane bridge, which gives extra stability to the maleimide group. Both enzyme activity and antibody specificity are preserved after coupling.
      Catalogue Number573115
      Brand Family Calbiochem®
      SynonymsSulfo-SMCC, Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate
      References
      ReferencesD’Souza, S.E., et al. 1988. J. Biol. Chem. 263, 3943.
      Product Information
      CAS number92921-24-9
      FormOff-white solid
      Hill FormulaC₁₆H₁₇N₂O₉S · Na
      Chemical formulaC₁₆H₁₇N₂O₉S · Na
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥94% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing each use, purge the original vial with inert gas and refrigerate (4°C). Unstable in aqueous solution; reconstitute just prior to use. Alternatively, the solid SMCC can be added directly to the sample to minimize hydrolysis. Hydrolysis is more pronounced in dilute protein solutions and can, therefore, be minimized by using more concentrated protein solutions (>5 mg/ml). For storage of stock solutions, reconstitute in anhydrous DMSO.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      573115-50MG 04055977266047

      Documentation

      SMCC, Water-Soluble Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      SMCC, Water-Soluble Certificados de análisis

      CargoNúmero de lote
      573115

      Referencias bibliográficas

      Visión general referencias
      D’Souza, S.E., et al. 1988. J. Biol. Chem. 263, 3943.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsSulfo-SMCC, Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate
      DescriptionA water-soluble derivative of SMCC. Ideal for coupling enzymes to antibodies. Contains a cyclohexane bridge, which gives extra stability to the maleimide group. Both enzyme activity and antibody specificity are preserved after coupling. Water-soluble cross-linking reagents help to avoid the use of organic solvents such as dimethylformamide (DMF) and dimethylsulfoxide (DMSO) when preparing bioconjugates.
      FormOff-white solid
      CAS number92921-24-9
      Chemical formulaC₁₆H₁₇N₂O₉S · Na
      Structure formulaStructure formula
      Purity≥94% by HPLC
      SolubilityH₂O (2-5 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing each use, purge the original vial with inert gas and refrigerate (4°C). Unstable in aqueous solution; reconstitute just prior to use. Alternatively, the solid SMCC can be added directly to the sample to minimize hydrolysis. Hydrolysis is more pronounced in dilute protein solutions and can, therefore, be minimized by using more concentrated protein solutions (>5 mg/ml). For storage of stock solutions, reconstitute in anhydrous DMSO.
      Toxicity Irritant
      ReferencesD’Souza, S.E., et al. 1988. J. Biol. Chem. 263, 3943.