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MBNMAG-41K MILLIPLEX MAP Mouse Bone Magnetic Bead Panel - Bone Metabolism Multiplex Assay

MBNMAG-41K
Design And Price Your Kit

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
ACTH DKK-1 FGF-23 IL-6 Insulin Leptin Osteoprotegerin SOST TNF-α MMplexLuminex xMAP
Description
Catalogue NumberMBNMAG-41K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Mouse Bone Magnetic Bead Panel - Bone Metabolism Multiplex Assay
Background InformationThe Milliplex® MAP Mouse Bone Magnetic Bead Panel contains all the components necessary to measure 9 biomarkers in any combination: ACTH (Adrenocorticotropic hormone), DKK-1 (Dickkopf-1), IL-6, Insulin, Leptin, TNFα, OPG (Osteopotegrin), SOST (Sclerostin) and FGF-23 in any combination. The kit uses a 96-well format, contains a lyophilized standard cocktail, 2 quality controls and can measure up to 38 serum or plasma samples in duplicate.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Inter-assay: < 15
  • Intra-Assay: < 10
Panel TypeMAGNETIC Bone
Quality LevelMQ200
Applications
ApplicationThe analytes available for this multiplex kit are: ACTH, DKK-1, FGF-23, IL-6, Insulin, Leptin, Osteoprotegerin, SOST, TNF-α.
Key Applications
  • Multiplexing
Application NotesRecommended Sample Dilutions:
Serum and plasma samples require (recommend) a 1:2 dilution with Assay Buffer.Each well requires 25uL of sample, standard or control. Tissue culture supernatants can also be used and if needed, make appropriate dilutions with control medium.
Biological Information
Species Reactivity
  • Mouse
Analytes Available
  • ACTH
  • DKK-1
  • FGF-23
  • IL-6
  • Insulin
  • Leptin
  • Osteoprotegerin
  • SOST
  • TNF-α
Assay PanelEverything you need in a single kit.
Accuracy
  • 84% - 94%
Physicochemical Information
Sensitivity
  • See kit protocol for individual analytes sensitivities.
Linearity of DilutionContact technical support for this information
Standard Curve Range
  • ACTH: 4-15,000 pg/mL
  • DKK-1: 15-60,000 pg/mL
  • IL-6: 7-30,000 pg/mL
  • Insulin: 37-150,000 pg/mL
  • Leptin: 10-40,000 pg/mL
  • TNFα: 3-12,000 pg/mL
  • OPG: 16-65,000 pg/mL
  • SOST: 3-12,000 pg/mL
  • FGF-23: 7-30,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

Documentation

Protocols

Title
Protocol: Mouse Bone Magnetic Bead Panel --96-Well Plate Assay

MILLIPLEX MAP Mouse Bone Magnetic Bead Panel - Bone Metabolism Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

References

Reference overviewPub Med ID
Dextromethorphan inhibits osteoclast differentiation by suppressing RANKL-induced nuclear factor-κB activation.
Wu, K; Lin, TH; Liou, HC; Lu, DH; Chen, YR; Fu, WM; Yang, RS
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA  24  2201-14  2013

Show Abstract
23400250 23400250
Positive environmental modification of depressive phenotype and abnormal hypothalamic-pituitary-adrenal axis activity in female C57BL/6J mice during abstinence from chronic ethanol consumption.
Pang, TY; Du, X; Catchlove, WA; Renoir, T; Lawrence, AJ; Hannan, AJ
Frontiers in pharmacology  4  93  2013

Show Abstract
23898297 23898297

Brochure

Title
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with Merck Millipore Immunoassay Platform Solutions.
Custom Immunoassay Menu of Services
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Ranges - Milliplex Mouse Bone Magnetic Bead Panel

Data Sheet

Title
Full Service Custom-built Assays (Merck)

Posters

Title
MILLIPLEX MAP: Exercise, Signaling, and Your Brain