W530098

Naringenin

Name: Naringenin
Brand: ALDRICH

natural (US), 98%

Synonym(s):

(±)-Naringenin, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyflavanone

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All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₂O₅

CAS Number:

67604-48-2

Molecular Weight:

272.25

PubChem Substance ID:

329830749

UNSPSC Code:

12164502

FEMA Number:

4797

NACRES:

NA.21

EC Number:

266-769-1

MDL number:

MFCD00006844

organoleptic:

faint

grade:

natural (US)

biological source:

Citrus paradisi Macf.

food allergen:

no known allergens

Product Name

Naringenin, natural (US), 98%

InChI

1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChI key

FTVWIRXFELQLPI-UHFFFAOYSA-N

SMILES string

OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O

biological source

Citrus paradisi Macf.

grade

natural (US)

assay

98%

mp

247-250 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

Quality Level

300

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Related Categories

Chemistry & Biochemicals

Flavors & Fragrances

Application

Naringenin has been used in a study to compare its antigenotoxic and antioxidative activity with that of naringenin-oxime.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

General description

Naringenin is a bioactive flavonoid found in citrus and grapefruit.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Naringenin inhibits migration, invasion, induces apoptosis in human lung cancer cells and arrests tumour progression in vitro.

Xingyuan Shi et al.

Journal of cellular and molecular medicine, 25(5), 2563-2571 (2021-02-02)

Lung cancer is one of the major cause for high-death rate all over the world, due to increased metastasize and difficulties in diagnosis. Naringenin is naturally occurring flavonoid found in various fruits including tomatoes, citrus fruit and figs. Naringenin is

Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells

Kocyigit A, et al

Drug and Chemical Toxicology, 39(1), 66-73 (2016)

Integrated Transcript and Metabolite Profiles Reveal That EbCHI Plays an Important Role in Scutellarin Accumulation in Erigeron breviscapus Hairy Roots.

Ruibing Chen et al.

Frontiers in plant science, 9, 789-789 (2018-07-18)

Scutellarin, a flavonoid 7-O-glucuronide, is an essential bioactive compound of Erigeron breviscapus (Vaniot) Hand.-Mazz. used for the treatment of cerebrovascular diseases. However, due to overexploitation and overuse, E. breviscapus is facing the problems of extinction and habitat degradation. In this

Home processing of tomatoes (Solanum lycopersicum): effects on in vitro bioaccessibility of total lycopene, phenolics, flavonoids, and antioxidant capacity.

Senem Kamiloglu et al.

Journal of the science of food and agriculture, 94(11), 2225-2233 (2014-01-01)

In order to investigate the effect of home processing on the bioaccessibility of health-related constituents of tomatoes, total lycopene, phenolics, flavonoids and antioxidant capacity were determined from seven different tomato products using an in vitro gastrointestinal digestion model. Additionally, the

Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat.

Nada Oršolić et al.

European journal of nutrition, 53(5), 1217-1227 (2013-11-26)

Reactive oxygen species play a role in a number of degenerative conditions including osteoporosis. Flavonoids as phyto-oestrogens exert physiological effects against oxidative stress diseases. We developed a retinoic acid-induced bone loss model of rats to assess whether flavonoids and alendronate

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