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122564

Mechlorethamine hydrochloride

98%

Sinónimos:

2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride, Bis(2-Chloroethyl)methylamine, Bis(2-chloroethyl)methylamine, MBA hydrochloride, NM, Nitrogen mustard

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Fórmula lineal:
(ClCH2CH2)2NCH3·HCl
Número CAS:
55-86-7
Peso molecular:
192.51
NACRES:
NA.22
PubChem Substance ID:
24847496
UNSPSC Code:
12352100
EC Number:
200-246-0
MDL number:
MFCD00012517
Assay:
98%
Form:
solid
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Quality Level

100

assay

98%

form

solid

mp

108-111 °C (lit.)

solubility

H2O: very soluble, alcohol: soluble

functional group

amine, chloro

SMILES string

Cl.CN(CCCl)CCCl

InChI

1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChI key

QZIQJVCYUQZDIR-UHFFFAOYSA-N

Application

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem/physiol Actions

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

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Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCK7776
MKBW4481V
41796PJ
38697LJ
07118JJ

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