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Merck

1.00020

Acetona

for liquid chromatography LiChrosolv®

Sinónimos:

Dimethyl ketone, Propanone, 2-Propanone

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About This Item

Fórmula lineal:
CH3COCH3
Número CAS:
67-64-1
Peso molecular:
58.08
UNSPSC Code:
12191502
NACRES:
NA.03
EC Index Number:
200-662-2
MDL number:
MFCD00008765
Beilstein/REAXYS Number:
635680
grade:
HPLC grade
assay:
≥99.8% (GC)
technique(s):
HPLC: suitable
bp:
56 °C/760 mmHg (lit.)
vapor pressure:
184 mmHg ( 20 °C)

Nombre del producto

Acetona, for liquid chromatography LiChrosolv®

InChI

1S/C3H6O/c1-3(2)4/h1-2H3

SMILES string

CC(C)=O

InChI key

CSCPPACGZOOCGX-UHFFFAOYSA-N

grade

HPLC grade

vapor density

2 (vs air)

vapor pressure

184 mmHg ( 20 °C)

description

isocratic

product line

LiChrosolv®

assay

≥99.8% (GC)

form

liquid

autoignition temp.

465 °C (DIN 51794)

potency

5800 mg/kg LD50, oral (Rat)
20000 mg/kg LD50, skin (Rabbit)

expl. lim.

13.2 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.05% Water

evapn. residue

≤2.0 mg/L

transmittance

335 nm, ≥50%
340 nm, ≥80%
350 nm, ≥98%

refractive index

n20/D 1.359 (lit.)

pH

5-6 (20 °C, 395 g/L in H2O)

capacity

1000  g/kg water absorbing capacity

bp

56 °C/760 mmHg (lit.)

mp

−94 °C (lit.)

transition temp

flash point <-20 °C

density

0.791 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-30°C

Quality Level

100

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Application

La intensidad de luminiscencia de la acetona depende de los componentes de la disolución . La absorción de luz ultravioleta por la acetona tiene como consecuencia su fotólisis y la producción de radiales .
Intended for HPLC and UHPLC-MS applications, either as an extraction solvent or as a mobile phase.
Reported for use in LC–MS/MS investigations of:
  • blood plasma and serum samples fractionated on several chromatography sorbents
  • peptides in animal biological samples

Features and Benefits

  • suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
  • specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
—ESI/APCI (+) < 2 ppb
—ESI/APCI (-) < 10 ppb
  • lowest impurity profile: for interference-free baselines (test 2)
  • microfiltered through 0.2 μm filter (test 3) to provide:
—a long lifespan to filters and mechanical parts of HPLC systems
—reduced risk of column clogging

  • packed in borosilicate glass bottles for minimized metal ion contaminations
  • lowest levels of trace metal impurities for a minimum metal ion adduct formation
—<5 ppb
  • lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

General description

LiChrosolv® solvents show high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Preparation Note

Product filtered through a 0.2 μm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH066

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 1

flash_point_f

1.4 °F - closed cup

flash_point_c

-17.0 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Proteomics-based identification of hypoxia-sensitive membrane-bound proteins in rat erythrocytes
Sidorenko S, et al.
Journal of Proteomics, 184, 25-33 (2018)
Peptidome profiling dataset of ovarian cancer and non-cancer proximal fluids: Ascites and blood sera
Shender V, et al.
Data in Brief, 22, 557-562 (2019)
Peptidomics dataset: Blood plasma and serum samples of healthy donors fractionated on a set of chromatography sorbents
Arapidi G, et al.
Data in Brief, 18, 1204-1211 (2018)

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