G7504
Guanosine 3′,5′-cyclic monophosphate
≥98% (HPLC), powder, intracellular mediator
Sinónimos:
cGMP, cyclic GMP
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Fórmula empírica (notación de Hill):
C10H12N5O7P
Número CAS:
Peso molecular:
345.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
231-641-6
MDL number:
Servicio técnico
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Permítanos ayudarleNombre del producto
Guanosine 3′,5′-cyclic monophosphate, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
solubility
0.2 M NaHCO3: 50 mg/mL
storage temp.
−20°C
SMILES string
NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
InChI
1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
InChI key
ZOOGRGPOEVQQDX-UHFFFAOYSA-N
Biochem/physiol Actions
A major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides.
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Features and Benefits
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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