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U5625

Uridine 5′-diphosphoglucuronic acid ammonium salt

Name: Uridine 5&#8242;-diphosphoglucuronic acid ammonium salt
Brand: SIGMA

98-100%, from Saccharomyces cerevisiae, powder

Sinónimos:

UDP-GlcA, UDPGA, Uridine-diphosphate-glucuronic acid ammonium salt, Uridine[5′]diphospho[1]-α-D-glucopyranosuronic acid ammonium salt

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Fórmula empírica (notación de Hill):

C₁₅H₂₂N₂O₁₈P₂ · xNH₃

Número CAS:

43195-60-4

Peso molecular:

580.29 (free acid basis)

UNSPSC Code:

41106305

PubChem Substance ID:

24900657

NACRES:

NA.51

Assay:

98-100%

Biological source:

Saccharomyces cerevisiae, enzyme from bovine liver (catalase), enzyme from rabbit muscle (LDH)

Form:

powder

Solubility:

water: 50 mg/mL, clear, colorless

Storage temp.:

−20°C

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Propiedades

Nombre del producto

Uridine 5′-diphosphoglucuronic acid ammonium salt, 98-100%

Quality Segment

200

biological source

Saccharomyces cerevisiae, enzyme from bovine liver (catalase), enzyme from rabbit muscle (LDH)

assay

98-100%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

N.O[C@@H]1[C@@H](O)[C@H](O[C@@H]([C@H]1O)C(O)=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O

InChI

1S/C15H22N2O18P2.H3N/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25;/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26);1H3/t4-,6-,7+,8+,9-,10-,11+,12-,14-;/m1./s1

InChI key

WMWKTCPGFOEPBD-YGIWDPDDSA-N

Descripción

General description

Uridine 5′-diphosphoglucuronic acid (UDPGA) is a cofactor, synthesized from UDPglucose and nicotinamide adenine dinucleotide (NAD⁺) intracellularly by the catalytic activity of UDPglucose dehydrogenase. The concentration of UDPGA in a number of liver preparations ranges from 0.3-0.5 mM.

Application

Uridine 5′-diphosphoglucuronic acid ammonium salt has been used in the initiation of UDP-glucuronosyl transferase (UDGPT) assay towards ¹⁴C-testosterone in the liver S9 protein. It is suitable for use in UDGPT assay.

Biochem/physiol Actions

Uridine 5′-diphosphoglucuronic acid (UDGPA) is the glucuronic acid donor for the conjugation of bilirubin in the endoplasmic recticulum.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c