Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

203984 2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem

203984
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₄H₇NO₂57-71-6

Products

Catalogue NumberPackaging Qty/Pack
203984-500MG Plastic ampoule 500 mg
Description
OverviewAn inhibitor of skeletal and cardiac muscle contraction. A general reversible inhibitor of myosin ATPase in eukaryotes. A “chemical phosphatase,” which dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC50 = 18.3 nM). Also shown to induce Ca2+ release from canine cardiac sarcoplasmic reticulum (SR).
Catalogue Number203984
Brand Family Calbiochem®
SynonymsBDM
References
ReferencesPhillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154.
Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305.
Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.
Product Information
CAS number57-71-6
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₄H₇NO₂
Chemical formulaC₄H₇NO₂
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCa2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Primary Target IC<sub>50</sub>18.3 nM inhibiting Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Purity≥98% by GC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSEK3150000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem Certificates of Analysis

TitleLot Number
203984

References

Reference overview
Phillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154.
Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305.
Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-October-2017 JSW
SynonymsBDM
DescriptionAn inhibitor of skeletal and cardiac muscle contraction. A "chemical phosphatase" that dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC50 = 18.3 nM). Also shown to induce Ca2+ release from canine cardiac sarcoplasmic reticulum (SR).
FormWhite to off-white solid
CAS number57-71-6
RTECSEK3150000
Chemical formulaC₄H₇NO₂
Structure formulaStructure formula
Purity≥98% by GC
SolubilityMethanol (100 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesPhillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154.
Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305.
Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.