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104551 ACC2 Inhibitor, CD-017-0191 - Calbiochem

104551
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₀H₁₉N₃O₃S

Products

Catalogue NumberPackaging Qty/Pack
104551-10MG Glass bottle 10 mg
Description
OverviewA cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
Catalogue Number104551
Brand Family Calbiochem®
Synonyms2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
References
ReferencesMarjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.
Product Information
FormOff-white solid
Hill FormulaC₂₀H₁₉N₃O₃S
Chemical formulaC₂₀H₁₉N₃O₃S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥90% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

ACC2 Inhibitor, CD-017-0191 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

ACC2 Inhibitor, CD-017-0191 - Calbiochem Certificates of Analysis

TitleLot Number
104551

References

Reference overview
Marjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision23-February-2011 RFH
Synonyms2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
DescriptionA cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
FormOff-white solid
Chemical formulaC₂₀H₁₉N₃O₃S
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityDMSO (50 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMarjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.