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171601 Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem

171601
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₇₃H₁₁₈N₁₆O₂₇

Products

Catalogue NumberPackaging Qty/Pack
171601-500UG Plastic ampoule 500 μg
Description
OverviewA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
Catalogue Number171601
Brand Family Calbiochem®
SynonymsKTEETSEVN(stat)VAEF
References
ReferencesSinha, S., et al. 1999. Nature 402, 537.
Product Information
ATP CompetitiveN
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₇₃H₁₁₈N₁₆O₂₇
Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetAPP
Primary Target IC<sub>50</sub>30 nM against amyloid precursor protein (APP) β-secretase
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem Certificates of Analysis

TitleLot Number
171601

References

Reference overview
Sinha, S., et al. 1999. Nature 402, 537.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-April-2008 RFH
SynonymsKTEETSEVN(stat)VAEF
DescriptionA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
Purity≥98% by HPLC
SolubilityAqueous Buffers (pH 7.5) (1 mg/ml).
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSinha, S., et al. 1999. Nature 402, 537.