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178456 Apolipoprotein B, Human Plasma, Low-Density Lipoprotein

178456
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
178456-500UG Plastic ampoule 500 μg
Description
OverviewNative apolipoprotein B from human plasma. Produced by the liver, and is a dominant protein constituent of LDL that is also present in VLDL. Ligand for LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Mean serum concentration: 950 µg/ml. Higher levels are reported in familial hyperlipidemia, obesity, and diabetes.
Catalogue Number178456
Brand Family Calbiochem®
SynonymsApo B, Apo B-100
References
ReferencesJiang, X.C., et al. 2001. Nat. Med. 1, 847.
Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.
Product Information
FormSolid
FormulationLyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Apolipoprotein B, Human Plasma, Low-Density Lipoprotein SDS

Title

Safety Data Sheet (SDS) 

Apolipoprotein B, Human Plasma, Low-Density Lipoprotein Certificates of Analysis

TitleLot Number
178456

References

Reference overview
Jiang, X.C., et al. 2001. Nat. Med. 1, 847.
Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-December-2007 JSW
SynonymsApo B, Apo B-100
DescriptionNative apolipoprotein B from human plasma. Native apoplipoprotein B from human plasma. Dominant protein constituent of LDL and also present in VLDL. Ligand for the LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Produced by the liver. Mean serum concentration: 950 µg/ml.
FormSolid
FormulationLyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by SDS-PAGE
SolubilityH₂O or Aqueous Buffers. Please refer to the label for lot-specific reconstitution volume.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesJiang, X.C., et al. 2001. Nat. Med. 1, 847.
Zhou, M., et al. 1995. J. Biol. Chem. 270, 25220.
Sivaram, P., et al. 1993. J. Biol. Chem. 269, 9409.
Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.