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196872 BAY 11-7085 - CAS 196309-76-9 - Calbiochem

196872
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₁₃H₁₅NO₂S196309-76-9

Products

Catalogue NumberPackaging Qty/Pack
196872-10MG Plastic ampoule 10 mg
Description
Overview

This product has been discontinued.





We are offering BAY 11-7085 (Cat. No. B5681) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.






Has biological properties very similar to those of BAY 11-7082 (Cat. No. 196870). In addition, BAY 11-7085 shows potent anti-inflammatory properties in vivo.

Catalogue Number196872
Brand Family Calbiochem®
Synonyms(E)3-[(4-t-Butylphenyl)sulfonyl]-2-propenenitrile
References
ReferencesNi, H., et al. 2001. Br. J. Haematol. 115, 279.
Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.
Product Information
CAS number196309-76-9
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₃H₁₅NO₂S
Chemical formulaC₁₃H₁₅NO₂S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetTNF-α-inducible phosphorylation of IκBα
Primary Target IC<sub>50</sub>10 µM against TNF-α-inducible phosphorylation of IκBα
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

BAY 11-7085 - CAS 196309-76-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

BAY 11-7085 - CAS 196309-76-9 - Calbiochem Certificates of Analysis

TitleLot Number
196872

References

Reference overview
Ni, H., et al. 2001. Br. J. Haematol. 115, 279.
Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.

Citations

Title
  • Zachary T. Resch, et al. (2005) Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts. Endocrinology 147, 885-890.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision03-April-2008 RFH
    Synonyms(E)3-[(4-t-Butylphenyl)sulfonyl]-2-propenenitrile
    DescriptionExhibits biological properties similar to that of BAY 11-7082 (Cat. No. 196870). BAY 11-7085 has also been shown to have potent anti-inflammatory properties in vivo.
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number196309-76-9
    Chemical formulaC₁₃H₁₅NO₂S
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO (10 mg/ml)
    Storage +2°C to +8°C
    Protect from light
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    Toxicity Standard Handling
    ReferencesNi, H., et al. 2001. Br. J. Haematol. 115, 279.
    Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.
    Citation
  • Zachary T. Resch, et al. (2005) Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts. Endocrinology 147, 885-890.