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197225 Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem

197225
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₅₀H₂₃₄N₄₄O₄₂S

Products

Catalogue NumberPackaging Qty/Pack
197225-1MG Plastic ampoule 1 mg
Description
OverviewA cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.
Catalogue Number197225
Brand Family Calbiochem®
Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
References
ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.
Product Information
ATP CompetitiveN
FormOff-white solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₅₀H₂₃₄N₄₄O₄₂S
Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetA negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control - Calbiochem Certificates of Analysis

TitleLot Number
197225

References

Reference overview
Wang, J-L., et al. 2000. Cancer Res. 60, 1498.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2008 RFH
Synonymscpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
DescriptionA cell-permeable, mutated cpm-1285 peptide analog where Leu151 is replaced by Ala. Does not induce apoptosis and displays about 15 fold lower Bcl-2 binding. Suitable for use as a negative control.
FormOff-white solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₅₀H₂₃₄N₄₄O₄₂S
Peptide SequenceCH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
Purity≥95% by HPLC
SolubilityDMSO (10 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
Toxicity Standard Handling
ReferencesWang, J-L., et al. 2000. Cancer Res. 60, 1498.