An invalid quantity was specified. The product quantity has been adjusted.
|208923-5MG||Glass bottle||5 mg|
|Overview||A pyrimidinyl sulfonamide compound that acts as a potent, reversible and CaM non-competitive inhibitor of CaMKII activities (IC50 = 0.063 µM) with excellent selectivity over several kinases (IC50 = >60, 36, 11, 30 and 21 µM for CaMKIV, MLCK, p38α, Akt1 and PKC, respectively). Shown to exhibit ~25-fold greater potency towards CaMKII than the CaM-competitive inhibitor KN-93 (Cat. No. 422708).|
|Synonyms||Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor XII|
|References||Asano, S., et al. 2010. Bioorg. Med. Chem. Lett. 20, 6696.|
|Structure formula Image|
|Purity||≥99% by HPLC|
|Safety Information according to GHS|
|Product Usage Statements|
|Packaged under inert gas||Packaged under inert gas|
CaMKII Inhibitor XII - Calbiochem SDS
|Asano, S., et al. 2010. Bioorg. Med. Chem. Lett. 20, 6696.|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.