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218829 Caspase-3 Substrate IX, Fluorogenic - Calbiochem

218829
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Products

Catalogue NumberPackaging Qty/Pack
218829-1MG Plastic ampoule 1 mg
Description
OverviewA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photostable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Useful for high throughput screening applications.
Catalogue Number218829
Brand Family Calbiochem®
Synonyms(Z-DEVD)₂-Rh 110
References
ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.
Product Information
ATP CompetitiveN
FormYellow lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₇₂H₇₈N₁₀O₂₇
Chemical formulaC₇₂H₇₈N₁₀O₂₇
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetA highly sensitive, photostable caspase-3 fluorogenic substrate
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Caspase-3 Substrate IX, Fluorogenic - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Caspase-3 Substrate IX, Fluorogenic - Calbiochem Certificates of Analysis

TitleLot Number
218829

References

Reference overview
Hug, H., et al. 1999. Biochemistry 38, 13906.
Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-June-2008 RFH
Synonyms(Z-DEVD)₂-Rh 110
DescriptionA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photo-stable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Also reported to detect capase-3 activity in intact cells by flow cytometry. Useful for high throughput screening applications. Excitation max: ~485 nm; emission max: ~535 nm.
FormYellow lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₇₂H₇₈N₁₀O₂₇
Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Purity≥95% by HPLC
SolubilityDMSO (1 mg/ml)
Storage -20°C
Protect from moisture
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.