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251600 Daidzein - CAS 486-66-8 - Calbiochem

251600
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₁₅H₁₀O₄486-66-8

Products

Catalogue NumberPackaging Qty/Pack
251600-25MG Plastic ampoule 25 mg
Description
OverviewInactive analog of Genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).
Catalogue Number251600
Brand Family Calbiochem®
Synonyms4ʹ,7-Dihydroxyisoflavone, Casein Kinase II Inhibitor X
References
ReferencesGuo, J-M., et al. 2004. World J. Gastroenterol. 10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol. 7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem. 262, 5592.
Product Information
CAS number486-66-8
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₅H₁₀O₄
Chemical formulaC₁₅H₁₀O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMiaPaC-2, PANC-1
Primary Target IC<sub>50</sub>45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSDJ3100040
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 24-26

Avoid contact with skin.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Daidzein - CAS 486-66-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Daidzein - CAS 486-66-8 - Calbiochem Certificates of Analysis

TitleLot Number
251600

References

Reference overview
Guo, J-M., et al. 2004. World J. Gastroenterol. 10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol. 7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem. 262, 5592.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-April-2008 RFH
Synonyms4ʹ,7-Dihydroxyisoflavone, Casein Kinase II Inhibitor X
DescriptionInactive analog of genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC50 >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number486-66-8
RTECSDJ3100040
Chemical formulaC₁₅H₁₀O₄
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (200 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
Merck USA index14, 2801
ReferencesGuo, J-M., et al. 2004. World J. Gastroenterol. 10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol. 7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem. 262, 5592.