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253300 Deltamethrin - CAS 52918-63-5 - Calbiochem

253300
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₂₂H₁₉Br₂NO₃52918-63-5

Products

Catalogue NumberPackaging Qty/Pack
253300-10MG Glass bottle 10 mg
Description
OverviewSynthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 100 pM). May also have varied effects on ion channels. Causes an increase in neurotransmitter release at synapses, and increases intrasynaptosomal Ca2+ levels.
Catalogue Number253300
Brand Family Calbiochem®
Synonyms(S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
References
ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
Product Information
CAS number52918-63-5
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₂H₁₉Br₂NO₃
Chemical formulaC₂₂H₁₉Br₂NO₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationDeltamethrin, CAS 52918-63-5, is a synthetic type II pyrethroid that acts as a potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 100 pM).
Biological Information
Primary Targetprotein phosphatase 2B
Primary Target IC<sub>50</sub>100 pM against calcineurin (protein phosphatase 2B)
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGZ1233000
Safety Information
R PhraseR: 21-23-28

Harmful in contact with skin.
Toxic by inhalation.
Very toxic if swallowed.
S PhraseS: 26-36/37/39-45-53

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid acid or alkali conditions.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Deltamethrin - CAS 52918-63-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Deltamethrin - CAS 52918-63-5 - Calbiochem Certificates of Analysis

TitleLot Number
253300

References

Reference overview
Richter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-December-2007 JSW
Synonyms(S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
DescriptionSynthetic type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 100 pM). May also have varied effects on ion channels. Causes an increase in neurotransmitter release at synapses and also increases intrasynaptosomal Ca2+ levels.
FormWhite solid
CAS number52918-63-5
RTECSGZ1233000
Chemical formulaC₂₂H₁₉Br₂NO₃
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (15 mg/ml) or Ethanol (1 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid acid or alkali conditions.
Toxicity Highly Toxic
Merck USA index14, 2883
ReferencesRichter, A., et al. 1995. Biochem. Pharmacol. 49, 367.
Enan, E., and Matsumura, F. 1993. Biochem. Pharmacol. 45, 703.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol. 43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci. 13, 236.