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324696 Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem

324696
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Overview

Replacement Information

Key Spec Table

Products

Catalogue NumberPackaging Qty/Pack
324696-10MG Glass bottle 10 mg
Description
OverviewA specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.
Catalogue Number324696
Brand Family Calbiochem®
References
ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
Product Information
CAS number70967-90-7
ATP CompetitiveN
FormLyophilized
FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
Hill FormulaC₂₇H₃₈N₆O₉
Chemical formulaC₂₇H₃₈N₆O₉
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetChromogenic substrate for human neutrophil elastase
Primary Target IC<sub>50</sub>Kcat/Km = 120,000 vs. 2700 for pancreatic elastase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem Certificates of Analysis

TitleLot Number
324696

References

Reference overview
Barrett, A.J., et al. 1989. Biochim. J. 260, 259.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-May-2008 JSW
DescriptionSpecific chromogenic substrate for human neutrophil elastase (kcat/Km = 120,000 versus pancreatic elastase: kcat/Km = 2,700). Cleavage can be monitored at 410 nm using ε = 8,800.
FormLyophilized
FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
CAS number70967-90-7
Chemical formulaC₂₇H₃₈N₆O₉
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.