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05-23-3801 Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem

05-23-3801
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
117399-93-6C₁₂₁H₁₆₈N₂₆O₃₃S₄

Products

Catalogue NumberPackaging Qty/Pack
05-23-3801-0.5MG Plastic ampoule .5 mg
Description
OverviewAttenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
Catalogue Number05-23-3801
Brand Family Calbiochem®
SynonymsET-3, CTCFTYKDKECVYYCHLDIIW
References
ReferencesGresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
Xin, X., et al. 1995. Endocrinology 136, 132.
Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.
Product Information
CAS number117399-93-6
ATP CompetitiveN
FormSolid
FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
Hill FormulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
Chemical formulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetStimulator of interleukin-6 production by endothelial cell lines
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-3801

References

Reference overview
Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
Xin, X., et al. 1995. Endocrinology 136, 132.
Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
SynonymsET-3, CTCFTYKDKECVYYCHLDIIW
DescriptionAttenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phopholipase C in fibroblasts expressing ETA receptors.
FormSolid
FormulationSupplied as a trifluoroacetate salt. Sold on the basis of peptide content.
CAS number117399-93-6
Chemical formulaC₁₂₁H₁₆₈N₂₆O₃₃S₄
Peptide SequenceH-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
Purity≥97% by HPLC
Solubility5% Acetic acid (0.5 mg/ml). Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with cold water to 5% acetic acid and 0.5 mg/ml peptide.
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
ReferencesGresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169.
Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
Xin, X., et al. 1995. Endocrinology 136, 132.
Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291.
Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.