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341283 Factor P, Human

341283
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
341283-250UG Plastic ampoule 250 μg
Description
OverviewNative factor P from human serum. Glycoprotein found in blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of 92 kDa, 138 kDa, and 184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
Catalogue Number341283
Brand Family Calbiochem®
SynonymsProperdin
References
ReferencesPangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
Product Information
FormLiquid
FormulationIn PBS, pH 7.2.
Quality LevelMQ100
Applications
Biological Information
Purity≥90% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Factor P, Human SDS

Title

Safety Data Sheet (SDS) 

Factor P, Human Certificates of Analysis

TitleLot Number
341283

References

Reference overview
Pangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-June-2008 RFH
SynonymsProperdin
DescriptionNative factor P from human serum. Glycoprotein found in circulating blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of ~92 kDa, ~138 kDa, and ~184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
FormLiquid
FormulationIn PBS, pH 7.2.
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥90% by SDS-PAGE
ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
Storage ≤ -70°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesPangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.