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341578 Fibrinogen, Plasminogen-Depleted, Human Plasma

341578
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
341578-500MG Glass bottle 500 mg
Description
OverviewNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Contains ≥ 95% clottable proteins.
Do not disturb until the fibrinogen is completely solubilized.
Catalogue Number341578
Brand Family Calbiochem®
References
ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.
Product Information
CAS number9001-32-5
FormLyophilized
FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
Quality LevelMQ200
Applications
ApplicationPlasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins.
Biological Information
Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Harmful
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Fibrinogen, Plasminogen-Depleted, Human Plasma SDS

Title

Safety Data Sheet (SDS) 

Fibrinogen, Plasminogen-Depleted, Human Plasma Certificates of Analysis

TitleLot Number
341578

References

Reference overview
Wang, H., et al. 1995. J. Infect. Dis. 171, 85.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-September-2007 RFH
DescriptionNative fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgery trauma, or in cases of myocardial infarction. It is found at decreased levels in cases of liver cirrhosis and serum hepatitis. The plasminogen was depleted using a Lys-agarose column.
FormLyophilized
FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9001-32-5
Purityhomogeneous by SDS-PAGE. Clottable proteins: ≥95%
SolubilityH₂O (25 mg/ml). To prevent clot formation, warm the H₂O and the fibrinogen to 37°C prior to dissolution.
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.
Toxicity Harmful
Merck USA index14, 4071
ReferencesWang, H., et al. 1995. J. Infect. Dis. 171, 85.