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345744 Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem

345744
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₅H₁₆₂N₅O₄₇ · 3NH₄

Products

Catalogue NumberPackaging Qty/Pack
345744-1MG Plastic ampoule 1 mg
Description
OverviewInhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.
M.W. 2180.5 (based on stearoyl - 18:0).
Catalogue Number345744
Brand Family Calbiochem®
SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
References
ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
Warren, L. 1959. J. Biol. Chem. 234, 1971.
Product Information
ATP CompetitiveN
FormLyophilized
Hill FormulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetInhibits Con A-stimulated mitogenesis in murine T cells
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem Certificates of Analysis

TitleLot Number
345744

References

Reference overview
Hakomori, S. 1985. Cancer Res. 45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
Warren, L. 1959. J. Biol. Chem. 234, 1971.

Brochure

Title
Gangliosides Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-July-2009 JSW
SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
DescriptionTrisialoganglioside prepared from bovine gray matter. Readily converted to GD1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.

Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
FormLyophilized
Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityEthanol or Methanol. For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity Irritant
ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
Warren, L. 1959. J. Biol. Chem. 234, 1971.