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106425 N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem

106425
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₅H₉NO₃S616-91-1

Products

Catalogue NumberPackaging Qty/Pack
106425-5GM Plastic ampoule 5 gm
Description
OverviewMucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
Catalogue Number106425
Brand Family Calbiochem®
SynonymsLNAC
References
ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
Product Information
CAS number616-91-1
FormWhite solid
Hill FormulaC₅H₉NO₃S
Chemical formulaC₅H₉NO₃S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by titration
Physicochemical Information
ContaminantsFe: ≤20 ppm
Cl: ≤ 0.04%
Sulfate: ≤ 0.03%
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSHA1660000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem Certificates of Analysis

TitleLot Number
106425

References

Reference overview
Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure

Citations

Title
  • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision01-May-2017 JSW
    SynonymsLNAC
    DescriptionA mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number616-91-1
    RTECSHA1660000
    Chemical formulaC₅H₉NO₃S
    Structure formulaStructure formula
    Purity≥98% by titration
    ContaminantsFe: ≤20 ppm
    Cl: ≤ 0.04%
    Sulfate: ≤ 0.03%
    SolubilityH₂O (50 mg/ml)
    Storage +15°C to +30°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
    Toxicity Standard Handling
    Merck USA index14, 88
    ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
    Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
    Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
    Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
    Citation
  • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.