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05-23-5501 Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

05-23-5501
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
52232-67-4C₁₈₁H₂₉₁N₅₅O₅₁S₂

Products

Catalogue NumberPackaging Qty/Pack
05-23-5501-1MG Plastic ampoule 1 mg
Description
OverviewN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
Catalogue Number05-23-5501
Brand Family Calbiochem®
References
ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
Dua, K., et al. 1994. Exp. Physiol. 79, 401.
Product Information
CAS number52232-67-4
ATP CompetitiveN
FormWhite to off-white lyophilized solid
FormulationSupplied as an trifluoroacetate salt.
Hill FormulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetHomeostatic control of Ca2+ and phosphate metabolism
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-5501

References

Reference overview
Matsui, H., et al. 1995. Am. J. Physiol. 268, R21.
Dua, K., et al. 1994. Exp. Physiol. 79, 401.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision4-October-2018 JSW
DescriptionN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
FormWhite to off-white lyophilized solid
FormulationSupplied as an trifluoroacetate salt.
CAS number52232-67-4
Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
Purity≥95% by HPLC
Solubility5% acetic acid (1 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 7034
ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
Dua, K., et al. 1994. Exp. Physiol. 79, 401.