SYNTHIA® Retrosynthesis Software
Discovery at Your Fingertips
Expert-coded by chemists and engineered by computer scientists, SYNTHIA® allows scientists to quickly discover novel pathways for new and published target molecules.
Developed over a 21-year period, this SaaS based software platform develops synthetic routes using expert-coded rules based on proven chemical transformations. With a catalog of over 12 million commercially available starting materials and building blocks, SYNTHIA® provides access to a broad portfolio of available chemistry.
SYNTHIA® Lab
Imagine a world where every lab, regardless of size or budget, can access the same advanced retrosynthesis technology trusted by leading scientists. With the launch of SYNTHIA® Lab, that world is closer than ever.
SYNTHIA® Lab brings the power of computer-assisted retrosynthetic planning to academic groups and non-profit research teams, making it easier than ever to explore new synthetic pathways, accelerate discovery, and inspire innovation. SYNTHIA® Lab helps you design robust, creative routes for both new and published molecules—no matter your lab’s size.
Quickly Go From Imagining What’s Possible to Testing What’s Probable
With this bench-validated retrosynthetic planning software, successfully design and plan routes for target molecules based on your requirements.
- Select the type of retrosynthesis analysis to be performed and the target molecule from known and unknown compounds.
- Customize search parameters: set a price threshold, protecting group preferences, scoring functions, stop conditions, and many more options.
- Directly link to commercially available and known starting materials with price information and/or incorporate your custom inventory (patent pending).
- Easily filter, sort, compare, and analyze custom pathways by viewing detailed molecule structures or graphs to explore the most cost-effective routes to chemical targets.
SYNTHIA® Retrosynthesis Software
Quickly and efficiently scan hundreds of pathways to help
you identify the best option according to your needs.
Explore the most cost-effective routes to your target molecules
with state of the art visualization and filtering options.
Easily customize search parameters to eliminate or promote
reactions, reagents or classes of molecules.
Explore unique and innovative syntheses that may be unknown
for building your desired molecule.
Easily generate a list of commercially available starting materials for your synthesis.
Discover More with SYNTHIA® Retrosynthesis Software
Experience how SYNTHIA® retrosynthesis software enhances your expertise, saves time and reduces synthesis costs.
We offer customizable license packages and comprehensive support. Contact us now to learn more.
Technical Application Notes
- App Note Application Programming Interface
Assess synthetic accessibility scores (SAS) of thousands of virtual molecules in minutes.
- Automated synthesis planning and execution Part 1
Custom search configuration in SYNTHIA®enables Synple-executable routes
- Automated synthesis planning and execution Part 2
- Computer-Assisted Synthetic Route Optimization using SYNTHIA® Retrosynthesis Software
Various challenges and considerations exist when designing an efficient process for synthesizing a target compound depending upon the scope of the project and industry. SYNTHIA® retrosynthesis software is a powerful tool for organic chemists that employs expert coded chemistry rules to predict feasible routes starting from commercially available raw materials.
Proven & Published External Journal Articles
In successful laboratory validation of a retrosynthetic design software, SYNTHIA® found robust and reliable pathways that reduced synthetic steps, increased yields, and decreased costs for both known and novel targets.
Computer-Aided Retrosynthesis for Greener and Optimal Total Synthesis of a Helicase-Primase Inhibitor Active Pharmaceutical Ingredient
Artificial Intelligence for Retrosynthetic Planning Needs Both Data and Expert Knowledge
Empowering Drug Discovery: How AIDDISON™ and SYNTHIA© Are Transforming Molecular Design
Algorithmic Discovery of Tactical Combinations for Advanced Organic Syntheses
Reinforcing the Supply Chain of COVID-19 Therapeutics with Expert-coded Retrosynthetic Software
Artificial Intelligence for Retrosynthetic Planning Needs Both Data and Expert Knowledge
Related Resources
- Brochure: SYNTHIA® Retrosynthesis Software Overview
Discovery at Your Fingertips Accelerate synthesis design with SYNTHIA® Retrosynthesis Software
- Brochure: SYNTHIA® Retrosynthesis Software API
Connect SYNTHIA® with your preferred cheminformatics software for high-throughput pathway design & molecular synthesis assessment
- Flyer: SYNTHIA® Retrosynthesis Software Lab Manager BIG Picture
Reducing Risk and Improving Synthesis Outcomes in Drug Discovery with SYNTHIA® Retrosynthesis Software
- Brochure: Shortcut to Greener Pathways
Designing an efficient process for synthesizing a target compound with minimal environmental impact presents numerous challenges. Our powerful retrosynthesis software, SYNTHIA®, can greatly facilitate prediction of more sustainable synthetic routes, starting from commercially available raw materials.
Screenshots
Related Video
SYNTHIA® Shared Path Library
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