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505982 (-)-Quinpirole Hydrochloride - CAS 85798-08-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555

Primary Target: D₂
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
85798-08-9C₁₃H₂₁N₃•HCl
Description
Overview

This product has been discontinued.



A potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
Catalogue Number505982
Brand Family Calbiochem®
SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
References
ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
Product Information
CAS number85798-08-9
FormWhite powder
Hill FormulaC₁₃H₂₁N₃•HCl
Chemical formulaC₁₃H₂₁N₃•HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetD₂
Primary Target K<sub>i</sub>4.8 nM
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505982 0

Documentation

(-)-Quinpirole Hydrochloride - CAS 85798-08-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
OʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
SynonymsDopamine D₂ Receptor Agonist, Quinpirole, Quinpirole, LY-171,555, LY 171555
DescriptionA potent, selective dopamine D2 receptor agonist with a Ki value of 4.8 nM. Some D3(Ki = 24 nM) and D4 (Ki = 30 nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5 nM).
FormWhite powder
CAS number85798-08-9
Chemical formulaC₁₃H₂₁N₃•HCl
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (7.3 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesOʹNeill, C. et al. 2009. J. Neurochem. 108, 545.
Malmberg, A. and Mohell, N. 1995. J. Pharmacol. Exp. Ther. 274, 790.
Seeman, P. and Schaus, J. M. 1991. Eur. J. Pharmacol. 203, 105.